副主任医师、硕士导师、医学博士
专业方向：
肿瘤介入微创治疗，放射性粒子组织间植入肿瘤治疗
临床技能：
熟练掌握肿瘤介入相关知识，应用介入导管和影像导向技术治疗头、颈、胸、腹、盆腔等部位肿瘤，如采用射频、微波、冷冻技术消融灭活肿瘤，放射性粒子组织间永久植入及高强度聚焦超声(HIFU)治疗恶性实体肿瘤。同时熟练掌握肝癌的动脉栓塞化疗、脾功能亢进介入栓塞治疗、子宫肌瘤动脉栓塞微创治疗、胰腺癌动脉灌注化疗、胃肠肿瘤动脉灌注化疗，动脉药盒导管系统植入术，气管或食管内支架植入术，经皮肝穿刺胆道内外引流及胆道内支架植入术，血管内支架植入术治疗上腔静脉或下腔静脉阻塞综合症，经皮穿刺椎体成形术，经皮穿刺活检术以及经导管DSA血管造影诊断等技术。
专业兼职：
中国抗癌协会肿瘤微创治疗专业委员会委员
中国抗癌协会粒子治疗学会委员
广东省抗癌协会肿瘤影像与介入诊治专业委员会委员
《Surgery》 Reviewer
《Am J Clin Oncol》 Reviewer
《Hepatology International》 Reviewer
近年发表SCI论文:
第一及通讯作者：
1. Noninvasive treatment of malignant bone tumors using high-intensity focused ultrasound. Cancer 2010;116(16):3934-42
2. Reply to high-intensity focused ultrasound (HIFU) is not indicated for treatment of primary bone sarcomas. Cancer 2011;117(15):2822-23.
3. Therapeutic effects and prognostic factors in high-Intensity focused ultrasound combined with chemoembolization for larger hepatocellular carcinoma. Eur J Cancer 2010;46:2513-21.
4. Efficacy of therapy for hepatocellular carcinoma with portal vein tumor thrombus: Chemoembolization and stent combined with iodine-125 seed. Cancer Biol Ther 2011;10 (12). In press
5. Feasibility of 125I brachytherapy combined with sorafenib treatment in patients with multiple lung metastases after liver transplantation for hepatocellular carcinoma. J Cancer Res Clin Oncol. 2010;136(11):1491-9.
6. Microwave ablation treatment of liver cancer with 2450-MHz cooled-shaft antenna: an experimental and clinical study. J Cancer Res Clin Oncol 2010;136:1507-16 (通讯作者)
7. Osteosarcoma: Limb salvaging treatment by ultrasonographically guided high intensity focused ultrasound. Cancer Biol Ther 2009;8(12):1102-8.
8. Superficial malignant tumors: Non-invasive treatment with ultrasonographically guided high-Intensity focused ultrasound. Cancer Biol Ther 2009;8(24):74-81.
9. Analysis of clinical effect for liver cancer using high intensity focused ultrasound. World J Gastroenterology 2004;10(15):2201-4.
10. A meta-analysis of the prevalence of somatic mutations in the hMLH1 and hMSH2 genes in colorectal cancer. Colorectal Disease 2011. In press. (通讯作者)
11. Microwave ablation: results in ex vivo and in vivo porcine livers with 2450-MHz cooled-shaft antenna. Chin Med J 2011;124. In Press .(通讯作者)
第二作者
13. Short to mid term evaluation of CT-guided 125I brachytherapy on intra-hepatic recurrent tumors and/or extra-hepatic metastases after liver transplantation for hepatocellular carcinoma.Cancer Biol Ther 2009;8(7):585-90.
14. CT, MRI, and FDG-PET/CT imaging findings of abdominopelvic desmoplastic small round cell tumors: Correlation with histopathologic findings. Eur J Radiol 2011:80: 269-73.
15. CT guided 125iodine seed implantation for portal vein tumor thrombus in primary hepatocellular carcinoma. Chin Med J (Engl) 2008; 121(23):2410-4.
第三作者及其他
16. Computed tomography and magnetic resonance imaging findings of peripheral primitive neuroectodermal tumors of the head and neck. Eur J Radiol 2011:80(2):607-11.
17. CT-guided percutaneous microwave ablation of adrenal malignant carcinoma: preliminary results. Cancer 2011:26
18. Comprehensive sequential interventional therapy for hepatocellular carcinoma. Chin Med J(Engl) 2009;122(19):2292-8.
19. Aurora-A down regulates IkappaBalpha via Akt activation and interacts with insulin-like growth factor-1 induced phosphatidylinositol 3-kinase pathway for cancer cell survival. Mol Cancer 2009;8:95.
20. Comprehensive sequential interventional therapy for hepatocellular. carcinoma. Chin Med J (Engl) 2009:5;122(19):2292-8.
参编著作：
1.《2006消化系统肿瘤新进展》北京：人民卫生出版社，2006年第1版。
2.《肿瘤介入诊疗学》北京：科学出版社出版，2005年第1版。
科研项目：
1.主持:广东省自然科学基金(10451008901006151)，Aurora-A激酶靶向抑制剂VX-680联合Sorafenib治疗晚期肝癌的机制研究;
2.主持:卫生部科研基金(WKJ2006-1-007)，高强度聚焦超声治疗肿瘤综合评价;
3.主持:广东省卫生厅基金(51205026)，肝细胞癌介入治疗分子疗效及微转移研究;
4.主持:暨大重点实验室开放基金(A2006227)，动脉栓塞化疗与高强度聚焦超声联合治疗肝癌的临床研究;
5.参研:广州市科技计划项目(2007Z3-E0231)，生物可控降解型放射性粒子链和匹配的TPS研制及临床前应用研究。
联系电话：020-87343381 Fax：020-87343774
出诊时间：周三上午
